Abstract: Stem cells, are extraordinary kind of cells having unique ability of self-renewal, lineage differentiation and regeneration of damaged organ or parts of body. Stem cells experience asymmetric cell divisions, bringing forth two cells from each cell, one cell is alike to SCs in stemnessess whereas, other is differentiated into various lineage. These cells have been known for decades for their highest regenerative potential but their clinical applications remain delayed due to several unknown mechanisms of their actions. With the discovery of Cancer Stem Cells, it was described that understanding the stem cell biology is important for a proper way of cancer cure. Stem cells are successfully being transplanted in several clinical trials to treat the retinal disease, visual disorders including retinitis pigmentosa, Stargardt’s disease, wound healing, skin regeneration and age related macular degeneration. Their role in cancer progression is the hot debate of research by cell biologists as understanding their role will help to remove the hurdles in cancer therapy.

Published in Journal of Genes and Cells on December 29, 2020

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